Faces hold a substantial value for efective social interactions and sharing. Covering faces with masks, due to COVID-19 regulations, may lead to difculties in using social signals, in particular, in individuals with neurodevelopmental conditions. Daily-life social participation of individuals who were born preterm is of immense importance for their quality of life. Here we examined face tuning in individuals (aged 12.79 ± 1.89 years) who were born preterm and exhibited signs of periventricular leukomalacia (PVL), a dominant form of brain injury in preterm birth survivors. For assessing the face sensitivity in this population, we implemented a recently developed experimental tool, a set of Face-n-Food images bordering on the style of Giuseppe Arcimboldo. The key beneft of these images is that single components do not trigger face processing. Although a coarse face schema is thought to be hardwired in the brain, former preterms exhibit substantial shortages in the face tuning not only compared with typically developing controls but also with individuals with autistic spectrum disorders. The lack of correlations between the face sensitivity and other cognitive abilities indicates that these defcits are domain-specifc. This underscores impact of preterm birth sequelae for social functioning at large.Comparison of the fndings with data in individuals with other neurodevelopmental and neuropsychiatric conditions provides novel insights into the origins of defcient face processing.