Iran’s ‘resistance economy’ is sometimes presented as defensive strategy. Despite Washington’s ‘New Middle East’ wars and the rapid evaporation of expected benefits from the long JCPOA (nuclear deal) process, a certain illusion remains that a general ‘normalisation’ with the outside powers might still bring economic benefits to the country. Nevertheless, it remains true that, while Iran is a large country, pure self-sufficiency would impose physical limits. Therefore, the question that one may ask is what are the better economic opportunities for the nation’s economic growth? By engaging with the globalist and new regionalism debates, making parallels between Latin American and West Asian ntegration, and presenting examples from Iran’s previous experiences, this paper argues that the answer to the above-mentioned question lies in a resistance economy, which builds an economically integrated regional bloc. The article begins by demonstrating the false promises of global economic liberalism, and then locates Iran’s resistance economy principles in the context of the ‘new regionalism’ debates. This forms the basis for discussing the economic potential of West Asian integration. This research is an interpretive study, testing the economic liberal project with evidence, and then comparing it with contemporary regional initiatives.