The United Nations Sustainable Development Goals (SDGs), announced in September 2015, present a vision of achieving a higher level of human health and well-being worldwide by the year 2030. The SDG targets specific to water and sanitation call for more detailed monitoring and response to understand the coverage and quality of safely managed sources. It is hoped that improved monitoring of water and sanitation interventions will reveal more cost-effective and efficient ways of meeting the SDGs. In this paper, we review the landscape of approaches that can be used to support and improve on the water and sanitation targets SDG 6.1, “By 2030, achieve universal and equitable access to safe and affordable drinking water for all”, and SDG 6.2, “By 2030, achieve access to adequate and equitable sanitation and hygiene for all and end open defecation, paying special attention to the needs of women and girls and those in vulnerable situations”