Much of the excitement about mindfulness relates to the quickly expanding research foundations that include not only clinical effectiveness, but also the neurological impact of mindfulness practice. This cross-discipline, multifaceted evidence base has quickly mainstreamed mindfulness practice, moving meditation from a fringe mental health activity to a highly respected treatment option in less than a decade. Although research on specifi c, manualized mindfulness-based treatments with couples and families is limited, the extant research on mindfulness and its effects provides suffi cient support to consider mindfulness-informed therapy an emerging evidence-based practice (Patterson, Miller, Carnes, & Wilson, 2004 ) . The research base on mindfulness includes the effects of mindfulness on: • Physical health • Adult mental health • Couples: distressed and nondistressed • Children, adolescents, and families • The brain