The input, application, and transformation of intellectual property can significantly promote the economic development of a region, but the path and operation mechanism of intellectual property management on regional economic growth are not very clear. System dynamics theory was used to analyze the driving force and resistance of intellectual property management from macro to micro. With the help of system dynamics theory, equations were constructed to simulate the process path and force from intellectual property management to regional economic growth, and sensitivity analysis was used to find sensitive influencing factors in the system. The following conclusions were drawn: (1) intellectual property affects regional economic growth from the macro level, such as intellectual property investment, policies, and the construction of rules and regulations; (2) enterprises, whether in the industry, universities and research institutes, or in this system, are the main body to create innovative benefits and ultimately promote regional economic growth; (3) the continuous investment of intellectual property resources and the driving force of enterprise innovation are all sensitive factors of this system. The government should give full play to its functions and strengthen the management of intellectual property in order to enable the regional economy to obtain high quality development. Through the study of the cooperation between the subjects in the process of intellectual property management activities, the integration and allocation process of factors and resources has been researched, and revealing the action process and dynamic change process of technological innovation activities on economic growth also have been revealed.